Description

Megestrol acetate is a synthetic progestogen that affects the hypothalamic-pituitary system of the animal and blocks the secretion by the adenohypophysis of gonadotropic hormones (follicle-stimulating and luteinizing). Decreased levels of these hormones in the blood of animals lead to impaired testosterone synthesis in males, which provides an antiestrogenic effect on the gonads of animals, resulting in the suppression of sexual desire. In megestrol males, acetate also acts as a regulator of behavior.

After taking the recommended dose, sexual desire in animals resumes in 3-4 months.

Megestrol acetate is well absorbed in the gastrointestinal tract, metabolized in the liver, and excreted in the urine within 1-2 days.