Description

Sinulox RTU has a wide spectrum of bactericidal activity against most gram-positive and gram-negative microorganisms, including strains producing b-lactamase: Streptococcus spp., Staphylococcus spp., Corynebacterium spp., Clostridium spp., Bacillus anthracstis, Actinomyсherces. coli, Salmonella, Bordetella bronchiseptica, Campilobacter spp., Klebsiella, Proteus spp., Pasteurella, Fusobacterium necrophorum, Bacteroides, Haemophilus spp., Moraxella spp., Actinobacillus pleuropneumoniae and Actinobacillus pleuropneumoniae and Actinobacillus ligneresinobacillus.

Resistance to b-lactam antibacterial drugs is usually due to the ability of microorganisms to produce b-lactamase, an enzyme that destroys the b-lactam ring of an antibiotic before it can act on a bacterial cell.

Clavulanic acid, which is part of Sinulox RTU, inactivates b-lactamase and thereby restores the bacteria’s sensitivity to the bactericidal action of amoxicillin in concentrations that are easily achieved in animal tissues after administration of the drug.