Description

A combination of sulfonamides and trimethoprim with long-term antimicrobial action.

Iodoform decomposes under the influence of light, air, tissue enzymes, microorganisms, releasing molecular iodine. Iodine has antimicrobial, repellent, deodorant, absorbent effect, promotes granulation and wound cleansing. Iodine albuminates are formed on the surface of the wound, which gives an astringent and anesthetic effect, relieves irritation of receptors.

Sulfaguanidine is a broad-spectrum sulfa drug. Effective against gram-positive and gram-negative bacteria Actinomyces spp., E. coli, Clostridium spp., Salmonella spp., Proteus spp., Bacillus anthracis, Pasteurella spp., Haemophilus spp., Erysipelothrix rhusiopathiae, Actinobacillobacter spp., Fus. ., Moraxella spp., Vibrio spp., Staphylococcus spp., Streptococcus spp., Shigella spp., Corynebacterium spp., Klebsiella spp., Fusobacterium spp., Bordetella spp., Brucella spp., Mycoplasma spp. Mycoplasma The mechanism of action is associated with PABA and competitive inhibition of dihydropteroate synthetase, which leads to a violation of the synthesis of tetrahydrofolic acid, which is necessary for the synthesis of purines and pyrimidines.

Trimethoprim is a chemotherapeutic drug that has a bacteriostatic effect against gram-positive and gram-negative microorganisms E. coli, Enterobacter spp., Proteus spp., Klebsiella spp. Inhibits bacterial reductase, which converts dehydrofolic acid into tetrahydrofolic acid, which is necessary for the synthesis of purines and pyrimidines.

Fillers provide a drying effect, help reduce exudation and accelerate the regeneration of damaged tissues and wound healing.

1 g of the drug contains:
iodoform – 40 mg
sulfaguanidine – 50 mg
trimethoprim – 10 mg